eng Oriental Scientific Publishing Company Material Science Research India 0973-3469 2024-12-15 21 3 115 133 23142 article Manita Thakur 1 Ankita Sharma 1 Ajay Kumar 2 Arush Sharma 3 Swati Kumari 4 Ajay Sharma 1 Department of Chemistry, School of Basic and Applied Sciences, IEC University Baddi, Solan, India. Department of Chemistry, School of Basic and Applied Sciences, Maharaja Agrasen University, Himachal Pradesh, India. Department of Chemistry, School of Sciences, Baddi University of Emerging Sciences and Technology (BUEST), Himachal Pradesh, India. 5School of Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, HP India Department of Environmental Science, Central University of Jammu, Bagla (Rahya-Suchani), Samba, Jammu and Kashmir, India. The production of nanoparticles derived from plant extracts has attracted considerable attention due to their cost-effectiveness, eco-friendly nature, and effective performance in different applications such as wastewater treatment and biomedicine. The present research emphasizes the eco-friendly synthesis of a nano-hybrid structure consisting of punica granatum (PGE) extract with zinc, lead, and manganese (ZPM). It is designed for efficient degradation of Methylene blue (MB) in nano-hybrid water systems. Punica granatum incorporated Zinc, lead and manganese (PGE/ZPM) nanohybrid structure was characterized using various techniques including FTIR (Fourier-transform infrared spectroscopy), FESEM (Scanning electron microscopy) with elemental mapping, HRTEM (Transmission electron microscopy), XPS (X-ray photoelectron spectroscopy) XRD (X-ray diffraction), TGA (Thermogravimetric analysis) and UV-Vis spectroscopy. The study included a thorough investigation of the optimization parameters specifically analyzing the effects of pH, dye concentration and catalyst dosage. The results showed that under solar exposure, 83.68% of Methylene blue (MB) was removed within 3 hours. The degradation mechanism follows pseudo-first order kinetics and the highest rate of degradation of MB at pH 6.0 was determined to be k= 0.0159 min^-1. The photocatalyst was reused for five cycles, showing only a minor decline in degradation effectiveness. Antibacterial effectiveness of PGE, ZPM and PGE/ZPM was also assessed against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). In summary, the cost-effective and environmentally friendly method used to synthesize PGE/ZPM has proven to be a versatile photo-catalytic and antibacterial agent. https://www.materialsciencejournal.org/vol21no3/punica-granatum-based-ternary-metal-oxide-nanoparticles-degradation-of-methylene-blue-and-antimicrobial-study/ Anti-bacterial activity Methylene Blue Photocatalysis Punica granatum