eng Oriental Scientific Publishing Company Material Science Research India 0973-3469 2026-04-23 23 1 24063 article Samir Kumar Ghosh 1 Sankar Narayan Patra 2 Department of Biomedical Engineering, Netaji Subhas Engineering College, Kolkata Department of Electronics and Applied Instrumentation, Jadavpur University, Kolkata Nano hydroxyapatite and β tricalcium phosphate (HAp/β-TCP) composite materials with predesigned phase composition were successfully synthesized via solution combustion route using  calcium nitrate tetrahydrate, diammonium hydrogen phosphate and glycine as the fuel. The investigations revealed that combustion flame temperature and its duration depend on several process parameters, and both play a key role in finding out the characteristics of the synthesized powders. An optimal parametric setting was established using Taguchi’s design of experiments (DoE) technique to control flame temperature in terms of achieving the best product characteristics. It was found that the optimal parametric combination, consisting of batch size of 6 g,  total valence of reducing and oxidizing agent (fuel to oxidizer) ratio of 0.8 and starting furnace temperature of 500 °C, resulted nano sized HAp/β-TCP) composite powders with particle sizes less than 100 nm. https://www.materialsciencejournal.org/vol23no1/experimental-design-approach-to-optimize-ha-%ce%b2-tcp-nanocomposite-formation-by-solution-combustion-process/ ANOVA Combustion synthesis HAp/β-TCP composite Nanoparticle Optimization of reaction parameters Signal to noise ratio