eng Oriental Scientific Publishing Company Material Science Research India 0973-3469 2026-02-10 23 1 24042 article Naba Shaikh 1 Nutan Sadgir 1 Sunil Dhonnar 1 Department of Chemistry, Mahatma Gandhi Vidya mandir’ Loknete Vyankatrao Hiray Arts, Science, and Commerce College, Panchavati, Nashik, India Due to their unique physicochemical properties, iron oxide nanoparticles have become an interesting class of materials that can be used in various technological processes. This study highlights the production of hematite nanoparticles (Fe₂O₃) by the simple co-precipitation method using primary reactants that are iron(III) chloride hexahydrate (FeCl₃ 6H₂O) and ammonia solution. These nanomaterials were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The XRD analysis showed that the formation of crystalline Fe₂O₃ phase was successful and it had crystallite dimensions calculated as about 40 nm. FTIR analysis showed typical Fe-O bands vibrationally, which justified the creation of pure iron oxide structures. SEM micrographs exhibited the morphology of spherical particles and were made to behave as clusters at high temperatures of calcination. Also, the synthesized Fe₂O₃ nanoparticles possessed significant antimicrobial and antifungal efficacy against specific pathogenic strains, and this should suggest their future use in biomedical and environmental remediation processes. https://www.materialsciencejournal.org/vol23no1/facile-synthesis-and-comprehensive-characterisation-of-nanoparticles-of-fe2o3-and-further-study-of-their-antimicrobial-and-antimalarial-efficacy/ Antimalarial Antimicrobial Fe2O3 nanoparticles SEM XRD