Syntesis and Spectral Studies of Mixed Ligand Complexes of Chloropropamide /Gliclazide with Iron and Cobalt

eng Oriental Scientific Publishing Company Material Science Research India 0973-3469 2013-12-15 3 1 81 84 1372 article Syntesis and Spectral Studies of Mixed Ligand Complexes of Chloropropamide /Gliclazide with Iron and Cobalt

Co-ordination compounds of chloropropamide (CPM) N-Propyl-N-(Pchlorobenzene sulphonyl) urea (trade name, diabinese) and gliclazide (GCZ) 1 - (3 - azabicyclo [3,3,0] oct - 3yl) - 3 - (P - totyl sulphonyl) urea. (trade name, diamicron) are oral hypoglycemic were synthesize with iron(II) and cobalt(II), isolated in pure powderd form, yields are substantial. Stoichiometry suggest 1:1:1 ratio between drugs and metal ion. Analytical data of the complexes agrees with the compositions are C10H12ClN2O3S-Fe-C15H20N3O3S 2H2O and C10H12ClN2O3S-Co- C15H20N3O3S.2H2O The general structure assigned to these complexes is supported by infra-red and electronic spectral studies.

https://www.materialsciencejournal.org/vol3no1/syntesis-and-spectral-studies-of-mixed-ligand-complexes-of-chloropropamide-gliclazide-with-iron-and-cobalt/ Complexation chloropropamide gliclazide iron and cobalt