eng Oriental Scientific Publishing Company Material Science Research India 0973-3469 2010-02-20 7 2 487 490 2427 article Development and Validation of Novel Spectrophotometric Methods for the Determination of Ethacridine Lactate in Bulk E. Venumadhav 1 P. Sai Praveen 2 T. Neha 2 P. Bhargavi 2 G. Devela Rao 2 Cheif Operating Officer, Veeda CR, Ahmedabad, Gujarat, India. KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520 010, India.

Three simple and sensitive visible spectrophotometric methods (A-C) for the determination of Ethacridine Lactate in pure samples and pharmaceutical formulations are described. They are based on the formation of colored species by treating with Folin-Ciocalteau reagent (Method A, λmax 600nm) or 3-methyl 2-benzathiazolinone hydrazone in the presence of Ferric chloride (Method B,  λmax 580 nm), or 1, 10 Phenathroline in presence of Ferric chloride (Method C, λmax 490nm). These methods were extended to the analysis of pharmaceutical preparations and results are compound with the refernce method (USP).

 https://www.materialsciencejournal.org/vol7no2/development-and-validation-of-novel-spectrophotometric-methods-for-the-determination-of-ethacridine-lactate-in-bulk/ Spectrophotometry Ethacridine Pharmaceutical preparation