A Novel Thermo-Optic Analysis to Detect Photochemical Reaction of Salbutamol


G. Kirshnakumar1, K. K. Kutty2, K. Raju1, S. Mohanan1, H. T. Varghese3 and C. Y. Panicker4

1Department of Physics, University College, Thiruvananthapuram, (India).

2Department of Physics, College of Engineering, Thiruvananthapuram, (India).

3Department of Physics, Fatima Mata National College, Kollam, (India).

4Department of Physics, TKM College of Arts and Science, Kollam, (India).

DOI : http://dx.doi.org/10.13005/msri/040232

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ABSTRACT:

A new thermo-optic analysis has been used to detect the photochemical reactions in salbutamol, a drug used as anti asthmatic/bronchodilator. Certain derived optic parameters of pure medicine and that exposed to solar radiations have been determined as a function of temperature. Plots of these parameters versus temperature have been made. The nature of variation and the relative shift in the curves for the exposed samples compared with the unexposed ones have been used to study photochemical reactions. The results have been explained in the light of existing theories and confirmed using UV absorption spectra of the samples.

KEYWORDS:

hermo-optic analysis; non destructive method; photochemical reaction; salbutamol

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Article Publishing History
Received on: 23 Nov 2007
Accepted on: 24 Dec 2007


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ISSN

Print: 0973-3469, Online: 2394-0565


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